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J Diabetes Its Complications (2014) 28:399405
Jena Shaw Tronieri, senior research investigator at the University of Pennsylvanias Center for Weight and Eating Disorders and co-author of the study
3 COMT inhibitors, such as entacapone, opicapone, and tolcapone, and MAO-B inhibitors, such as selegiline, rasagiline, and safinamide, work by enhancing levodopas duration of action with inhibition of their respective enzymes
The study only employed a single drug dose, overlooking dose-dependent investigations, which will also be addressed in subsequent research
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