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17 The following domains were evaluated: confounding bias, selection of participants, classification of interventions, deviations from intended interventions, missing data, and measurement of outcomes

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This condition occurs approximately in about 5% of the population, however, among patients with cardiovascular diseases this condition occurs in up to 45% of patients and represents a serious risk of heart attack, endothelial dysfunction, arterial diseases, extracranial carotid artery disease, a common cause of the transient ischemic attack, termed also mini-stroke

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doi:10.1371/journal.pone.0056660 106

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