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Per CDC's 2019 Behavioral Risk Factor Surveillance System (explained in the article below), West Virginia had the highest rate of smoking in the country, at 23.8 %, followed by Kentucky, Louisiana, Ohio, Mississippi, Alabama, Arkansas, Tennessee, Missouri, Indiana, Oklahoma, and Michigan.

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Diabetes mellitus was defined as a history of diabetes, use of insulin or glucose-lowering medications, glycosylated hemoglobin 6.5%, fasting blood glucose 126 mg/dL, or 2-hour postprandial blood glucose 200 mg/dL

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H&E staining showed that after down-regulating the level of miR-125a-5p, the pathological manifestations of emphysema in the lungs of mice were reduced (Fig

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