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The main computations for CCM and S-map were performed using the rEDM package 104 , and all statistical analyses were performed in R version 4.4.1 105

Although the majority of participants were primarily involved in wheat farming and spraying was predominantly carried out by others with tractors, detailed information on their pesticide exposure was not available

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Treadmill stress tests were performed approximately 90 minutes after participants had either vaped or smoked and 90 minutes after those who reported no nicotine use had rested

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