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Effet sur la sant publique : la baisse de la consommation tend rduire les cots lis aux pathologies provoques par le tabac, qui cotent environ 47 milliards deuros annuellement au systme de sant franais

21 We now consider two distinct strategies for reshaping the market to restore law and order, support adults to quit smoking, and control youth uptake: Option 1: addressing the shadow economy primarily through enforcement Option 2: regularizing trade primarily through radically increased authorizations In practice, both will be required, but we strongly recommend focusing on Option 2 as the primary vehicle for restoring order and control to the US tobacco and nicotine marketplace

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We also performed Molecular Dynamics (MD) simulation to evaluate the intermolecular interactions during the period of the simulation