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Am J Epidemiol 2008, 167: 15-19

3a, blood samples from smokers incubated without any exogenous stimulus secreted significantly ( p 35 display a reduction in CD8 + and an increase in CD4 + T cells such that their CD4/CD8 ratio is more than double that of controls 20

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Disadvantages Sensitive to dust particles and insects, meaning that regular maintenance is needed