The primary risk factors for NAFLD include obesity (particularly central adiposity), type 2 diabetes mellitus , insulin resistance , dyslipidaemia (abnormal cholesterol levels), and metabolic syndrome
Research suggests that nicotine and other tobacco constituents may contribute to hepatic steatosis through several metabolic pathways
This decrease in function and immunity, paired with smokings tumor-promoting features, ultimately makes the liver vulnerable to disease and cancer
J Hepatol (2009) 51:53547.10.1016/j.jhep.2009.03.026 41 AzzaliniLFerrerERamalhoLNMorenoMDominguezMColmeneroJet alCigarette smoking exacerbates nonalcoholic fatty liver disease in obese rats
Additionally, nicotine and other chemicals may affect other organs, potentially impacting kidney and liver function over time.Being aware of these secondary health risks is just as important, as they compound the dangers of chewing tobacco use
Research indicates that smokers with NAFLD are more likely to develop advanced fibrosis (scarring) compared to non-smokers