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lncRNA: long non-coding RNA LP Lamina propria MIF Macrophage migration inhibitory factor MtTFA Mitochondrial transcription factor MMP14 Matrix metalloproteinases 14 MUC5AC Mucin 5AC, oligomeric mucus/gel-forming PRMT6 Protein arginine methyltransferase 6 PMVECs Pulmonary microvascular endothelial cells PBS Phosphate buffered saline RPMECs Rat pulmonary microvascular endothelial cells Rbm Reticular basement membrane ROS Reactive oxygen species RLMVECs Rat lung microvascular endothelial cells RAGE Receptor for advanced glycation end products SPDEF SAM-pointed domain-containing Ets-like factor TNF- Tumor necrosis factor- rhTNFR Fc: Recombinant human tumour necrosis factors receptor Fc fusion protein TLR4 Toll-like receptor 4 TGF-1 Transition transforming growth factor-beta 1 TSE Tobacco smoke extract VEGFA Vascular endothelial growth factor A VEGF Vascular endothelial growth factor

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