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Authors contributions Designed and conducted the study, performed data acquisition and analysis, and wrote the manuscript: Zhang W, Xue J Collected and managed data: Wang J, Ni D, Zhou W Performed data management: Wang B, Shi J Conceived and designed the study, conducted it, interpreted the data, and revised the manuscript: Wang A All the authors have read and approved the final version of this manuscript

Despite Ozempic and Mounjaro not being approved for weight loss, news of people rapidly losing weight spread, and off-label uses became more popular

This leads to reduced calorie intake and gradual weight loss

NMA = network meta-analysis