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Humberto Choi, a pulmonologist who leads the smoking cessation program at Cleveland Clinic, echoes these thoughts, stressing that the way IQOS is being marketed sounds like a similar strategy used by companies that previously pitched cigarettes and e-cigarettes to the public

Damaged skin produces a protein called collagen to repair itself

PMID 11396772

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This reduced blood flow can cause chest discomfort, and in more serious cases, it can lead to a heart attack or stroke if blood flow to the heart or brain is completely cut off