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[] A wide range of biomarkers, including spirometry, carbon monoxide levels, genetic variants linked to lung cancer risk, and atherosclerotic plaque imaging have been used for assessing smoking cessation

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According to Ken Marians, a DNA replication expert at SKI, an abundance of G-to-T tranversions in DNA is a hallmark of smoking-induced damage and has been dubbed the smoking signature. Different types of environmental factors cause different types of mutations