While Ozempic and other weight-loss drugs have been shown to have myriad benefits, they can also present some unwelcome effects, primarily nausea, vomiting and other gastrointestinal symptoms
Medications & Surgery Medications will typically focus on treating conditions like vaginitis, PCOS, or STDs that might be behind bleeding between periods
For example, the appetite and craving reduction effects aren't seen once the medication is stopped
To get closer to cause-and-effect answers, researchers conducted a target-trial emulation in 2025
Lowering BP to target cuts the rate of loss of eGFR in half, and adding a RAASi, as done in the Irbesartan Diabetic Nephropathy Trial, further reduced this rate considerably (Table 4)
Speaking with MNT , Megan Warnke, RDN, a registered dietician nutritionist and Certified Diabetes Care and Education Specialist, also not involved in this research, explained that a very low-calorie diet is not viable approach beyond a short-term intervention: The key words in this study are short term results. Like with any diet, this approach may work for a short period of time, but its not sustainable for long term results. Also, appetite suppression from semaglutide can help patients follow a calorie-restricted diet, but other factors like stress, sleep, and food insecurity will also impact diet success, which is something this drug cant fix, Warnke explained
