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[77] The ability of humans to change the genetics of animals took an enormous step forward in 1974 when Rudolf Jaenisch could produce the first transgenic mammal, by integrating DNA from simians into the genome of mice

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Lowering the transcript level in the NtZIP4A/B RNAi plants by around 40% resulted in decreased translocation of both Zn and Cd, but, interestingly, this effect depended on a combination of the concentrations of both metals

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