Bowie, A
In vitro , experimental results demonstrate that the ferroptosis inducers erastin and high glucose both induce ferroptosis in the mesangial cells of the glomeruli
Extra caution is important with: Frequent vomiting or suspected cannabinoid hyperemesis Symptoms of gastroparesis, including early fullness, nausea, vomiting, bloating, and upper abdominal pain Diabetes medications that can cause low blood sugar, including insulin or sulfonylureas Heavy cannabis use, high THC products, or unpredictable edibles dosing Prior dehydration, severe constipation, pancreatitis, or unexplained severe abdominal pain Very low appetite, unintended weight loss, or eating disorder history Multiple sedating substances Upcoming surgery, anesthesia, endoscopy, colonoscopy, or gastric emptying testing GLP-1 medications can delay gastric emptying, which also matters for procedures and anesthesia planning
These effects often develop gradually, which is why weight-related conditions can progress quietly before symptoms become noticeable Pfizer is committed to advancing scientific research aimed at better understanding weight-related conditions and discovering potential breakthroughs in weight management to help improve long-term health for people living with these conditions
Some of these medications have demonstrated cardiovascular benefits in specific populations
Your provider may suggest dose adjustments instead
