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Sustained remission: 12+ months without meeting SUD criteria per DSM-5

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For decades, traditional cigarettes reigned supreme, but shifting consumer preferences, heightened health awareness, and evolving regulatory pressures have accelerated a pivot towards what the industry terms reduced-risk products. This category encompasses a diverse range of alternatives, including modern oral nicotine pouches, e-cigarettes (vapes), and heated tobacco products

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de Leon J, Becona E, Gurpegui M, Gonzalez-Pinto A, Diaz FJ: The association between high nicotine dependence and severe mental illness may be consistent across countries

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