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Experimental validation Dose response curves and determination of IC 50 values were assessed for the 12 candidate drugs using 3-fold dilution series (see Supplementary Methods (Supplementary File 1) for more details)

Grejtakova D, Boronova I, Bernasovska J, Bellosta S

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Experiments need to be designed where the inhibitors/activators of the identified genes are administered simultaneously with various ASMs to evaluate the effects of their co-treatment

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stvold at the Department of Clinical Dentistry, Liv Kristine ysd and Torunn Eide, Department of Clinical Science, University of Bergen, for technical assistance