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Potentially effective initiatives with youth and young adults to prevent smoking were reviewed in the 2012 Surgeon Generals report and may be applicable to preventing e-cigarette use

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[16] According to The Merck Index , [17] the LD 50 of THC (the dose which causes the death of 50% of individuals) is 1270 mg/kg for male rats and 730 mg/kg for female rats from oral consumption in sesame oil, and 42 mg/kg for rats from inhalation

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