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Major Driver: Demand in regions where such products remain legal

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In this study, we performed a two-sample and mediation MR analysis using large-scale, publicly available genome-wide association study (GWAS) summary statistics

I know this sounds harsh, especially to smokers reading this while thinking Great, now Im not just unhealthy, Im also in spiritual bondage. But hear me out: Recognizing addiction as enslavement isnt condemnation