Agarwal A, Hamada A, Esteves SC
Beyond glucose regulation, tirzepatide significantly affects appetite and satiety through central nervous system pathways
Interestingly, these beneficial effects on inflammation and fibrosis, initially identified in models of diabetes, have now been extended to non-diabetic models of renal injury including the classical subtotal nephrectomy model (63), which had been used originally to define the renoprotective role of drugs that block the RAAS (69, 70)
S1A and S1B in the Supplementary Appendix)
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