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According to Ken Marians, a DNA replication expert at SKI, an abundance of G-to-T tranversions in DNA is a hallmark of smoking-induced damage and has been dubbed the smoking signature. Different types of environmental factors cause different types of mutations

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Medications such as bupropion, nortriptyline, varenicline, and clonidine may also be used

Though aspirin is approved for use in children older than age 3, children and teenagers recovering from chickenpox or flu-like symptoms should never take aspirin