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In many cancers, reduced MPC activity limits mitochondrial pyruvate uptake, dampens oxidative phosphorylation, and thereby fuels the Warburg effect [14]

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Remarkably, it exhibits minimal toxicity towards normal organs, highlighting its potential as a transformative ferroptosis inducer ( Certain small molecule monomers possess the ability to adjust SLC7A11 activity, thereby influencing intracellular GSH levels and potentially providing therapeutic advantages for treating specific tumors

Flavonoids prevent the progression of atherosclerosis by scavenging free radicals and activating antioxidant defenses (Nrf2-mediated), thereby reducing LDL oxidation and endothelial damage