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They include: depressed mood trouble sleeping difficulty concentrating feeling restless and jumpy irritability increased hunger or weight gain slower heart rate Symptoms of nicotine withdrawal typically peak within Your cravings are caused by nicotine receptors in the brain

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Reads were mapped to the GRCh38v93 version of the human genome and transcriptome [3] using the STAR RNA-seq alignment tool [4]

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Statistics show that as many as one in every 20 middle school students use e-cigarettes