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Machine smoking Five cigarettes for each sample (UF, CAF, PF and SMF) were smoked by using a Filtrona Model 302

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Am J Transl Res 8:18481856 Ma X, Jia Y, Zu S, Li R, Jia Y, Zhao Y, Xiao D, Dang N, Wang Y (2014) 5 Nicotinic acetylcholine receptor mediates nicotine-induced HIF-1 and VEGF expression in non-small cell lung cancer

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All studies that reported an increased risk of cancer assessed acute exposure effects to e-cigarettes (Figure 3)