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Clinical trials show impressive results: tirzepatide reduced the apnea-hypopnea index (AHI) by up to 63% approximately 30 fewer breathing interruptions per hour 33

Histological evidence of nephropathy was attenuated using dapagliflozin (another SGLT2 inhibitor), which reduces gene expression of inflammation and oxidative stress in the kidney of db/db mice

Contrave and Wegovy have different mechanisms and different levels of efficacy

For many, the benefits of the medication outweigh this potential, though still uncertain, risk

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It should only be considered under direct medical supervision