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Furthermore, recent real-world studies in Central and Eastern Europe have demonstrated cytisines high tolerability and adherence, reinforcing its role as a practical cessation aid 5
Finally, identified biomarkers of potential harm (in italics and dashed box) are also integrated in this conceptual framework as part of the conceptually-related domains, because they are on a causal pathway between TNP use and changes in health and functioning [133, 134]
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Researchers measured cardiac adrenaline activity by assessing heart rate variability and oxidative stress in blood samples by measuring the enzyme plasma paraoxonase
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