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The biology of the glucocorticoid receptor: new signaling mechanisms in health and disease

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There is increasing evidence for the involvement of microglial cells, which are the brain's primary homeostatic sensor, in drug dependence and its associated behavioral manifestations particularly in the adolescent brain

While the findings were consistent with the hypothesis that semaglutide might be beneficial for smoking cessation, the authors say study limitations preclude firm conclusions and should not be interpreted to justify clinicians use of semaglutide off-label for smoking cessation

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