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It was popularised as a way of warding off disease through the 17th, 18th and 19th centuries, including being used to give a smoke enema to revive victims of drowning along the River Thames

Additionally, to incorporate dose into our model, we converted a categorical smoking variable to be continuous which may increase noise in our estimates

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They estimate that at this time it was around 4 a.m

Mermelstein, PhD, Raymond Niaura, PhD, Kenneth A

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