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Furthermore, targeted delivery of exendin-4 to the nucleus of the solitary tract (NTS) similarly diminished both operant responding for sucrose under a progressive ratio schedule and conditioned place preference for food rewards in rats (Richard et al., 2015)

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Acetylcholine acts through five muscarinic receptors, however, on smooth muscle cell surface mainly M2 and M3 subtypes are expressed in the proportion of 35 to 1 ( Gastrointestinal dysfunction is a common finding among patients with T2DM

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