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Furthermore, metabolomic data corroborate these findings by showing the reactivation of fatty acid oxidation pathways and the reduction of lipotoxic intermediates

Hold the pen for a full 10 seconds before withdrawing

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In this context, DHODH, a mitochondrial inner-membrane enzyme traditionally known for its role in de novo pyrimidine biosynthesis, was proposed to also function as a CoQ 10 oxidoreductase and ferroptosis suppressor