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Common side effects for both include: Mild injection-site reactions (small bump or redness, resolves within hours) Transient water retention in the first 1-2 weeks Vivid dreams in the first week (often a positive sign of deepening REM cycles) Occasional brief flushing sensation immediately after injection more common with CJC-1295/Ipamorelin Mild tingling or fatigue in the first few doses, typically resolves quickly Less common but serious considerations include effects on glucose tolerance (worth monitoring if you're insulin-resistant or diabetic), the potential for joint discomfort if dose is too high, and any contraindications related to active cancer, severe pituitary issues, or specific medications

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Since CGRP increases production of insulin-like growth factor-I (IGF-I) in fetal osteoblasts in vitro, it is possible that sensory neuron activation by capsaicin increases production of IGF-1 [12]

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