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Therefore, targeting NRF2-related signaling pathways offers potential therapeutic strategies for inducing or inhibiting ferroptosis in various diseases, including cancer and neurodegenerative disorders (Yan et al., 2023)
It helps to restore the integrity of the tight junctions between intestinal cells, effectively "sealing the leaks." By healing the gut, we often see a dramatic reduction in systemic inflammation and a resolution of the symptoms it causes
FOXO4-DRI is a D-amino acid retro-inverso peptide that disrupts the intracellular interaction between FOXO4 and p53 in senescent cells, triggering p53-mediated apoptosis selectively in senescent rather than healthy proliferating cells
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