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However, one animal study has demonstrated that e-cigarette vapours can cause DNA changes in rat models which is the mechanism through which cancer develops. And even though the main cancer-causing chemicals (like tar) of tobacco smoke are absent in e-cigarettes, many other carcinogenic particles are still present

Those will be the times when the strongest nicotine withdrawal (i.e., cravings) will be experienced

Thomson D, Berk M, Dodd S, Rapado-Castro M, Quirk SE, Ellegaard PK, et al

31 : 197205 Phillips DH

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