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The BNF recently (2019) changed its guidance for the frequency of injections of hydroxocobalamin: Every 2 months in patients who have neurological symptoms Every 2 or 3 months when there are no neurological symptoms

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Its a 15-amino-acid peptide originally derived from a protective protein naturally found in human gastric juices, and it has been studied for more than 30 years by multiple independent research groupsmost notably teams in Croatia and Taiwan

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