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Its not so much the nicotine thats the primary issue

Some studies suggested that nicotine may regulate platelet activation by decreasing aggregation, thereby decreasing thrombosis [28], while other studies showed that nicotine has no effect on platelet activity [29]

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57 Studies have shown that stopping smoking will not lead to an exacerbation of schizophrenia symptoms 31 although there is some evidence to suggest that people with this disorder may experience more severe withdrawal symptoms during the first week of a quit attempt than other would-be quitters

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