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Add food noise on top of that, and it can feel exhausting

Based on the published literature on Nrf2, the rise of Nrf2 protein levels is likely due to impaired degradation of the Nrf2 protein, rather than an induction of its transcription or translation

Pharmacol Ther (2022) 239:108273

J.BoultJ.RobertsK.CooperB

373 Barbieri, C

3.2.3.1 -syn and tyrosine hydroxylase (TH) The abnormal aggregation of -syn, a core pathological hallmark of PD, disrupts ER homeostasis, inducing persistent ER stress and activating apoptotic pathways (13)