In adipose tissue, elevated NNMT activity is strongly correlated with obesity, insulin resistance, and cellular aging
Do glutathione supplements work better with Vitamin C
Increased proteolysis of insulin-like growth factor-binding protein-3 (IGFBP-3) in noninsulin-dependent diabetes mellitus serum, with elevation of a 29-kilodalton (kDa) glycosylated IGFBP-3 fragment contained in the approximately 130- to 150-kDa ternary complex
High-performance target: Below 0.5 mg/L
This combination is often discussed in wellness and regenerative medicine settings because patients are interested in tissue support, recovery support, mobility, and post-activity recovery
At the 0.25mg starting dose, you would be getting 0.375mg, not catastrophic but enough to trigger unnecessary side effects right from the beginning