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This is because they are thought to contain chemicals called congeners

(2015) Br J Cancer, 112: 580

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Transplantation (1990) 50(4):53744.10.1097/00007890-199010000-00001 59 MantovaniABussolinoFDejanaE

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However, for many Indigenous communities, tobacco continues to maintain its sacred status, and this is reflected in some of the ways native cigarettes are perceived and marketed today