This disruption may contribute to thyroid dysfunction and related symptoms, such as changes in weight, fatigue, and mood disturbances
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Hodgkinson J, Mant J, Martin U, Guo B, Hobbs FD, Deeks JJ, et al
High and slow to decline: the stress response staying active longer than expected, commonly associated with chronic stress and difficulty winding down Flat with a weak morning peak: associated with burnout, sustained fatigue, and depleted stress resilience Elevated in the evening: often connected to disrupted sleep, racing thoughts at bedtime, and stimulant or screen exposure late in the day Inverted (low in the morning, higher at night): a pattern associated with disrupted circadian rhythm, shift work, or significant lifestyle stress Adam EK, Quinn ME, Tavernier R, et al
So on the eve of 1920s smoking cigarettes was considered to be the destiny of women of low social responsibility, but Marlboro advertisements had feminine, glamorous images, not connected with the widespread prejudice in any way