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Then he lights it, and lets the chamber fill with smoke, where an anesthetized rat is exposed to the smoke

Another reason may be that smoking can lead to aggressive health conditions, including other cancers and heart and lung diseases, which may affect mortality before a prostate cancer diagnosis

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[23] Side effects of nicotine include mild headache, headache, dysphoria, depressed mood, irritability, aggression, frustration, impatience, anxiety, sleep disturbances, abnormal dreams, irritability, and dizziness