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The electronic cigarette, a small, thin, metallic tube that has become more popular in recent years, has also risen as an alternative to the standard tobacco cigarette

2014;4:e006141

Protective effect of beraprost sodium, a stablel prostacyclin analogue, in the development of cigarette smoke extract-induced emphysema

With repeated exposure, the brain upregulates (increases) the number of these receptors and becomes dependent on nicotine to maintain normal dopamine signaling

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