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The main pathological changes are found in the small airways with epithelial remodeling including goblet cell metaplasia, basal cell hyperplasia, leading to thickening of small airway walls and obliteration [4]

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Epidemiologists, doctors, geneticists and basic science researchers should work together to clarify the etiology. Although the potential risk factors for nonsmokers include exposure to secondhand smoke, outdoor air pollution, and indoor air pollution, such as that from burning wood, coal, other solid fuels, or kerosene for heat in poorly ventilated houses, these factors do not seem to be responsible for the rising lung cancer incidence in young female nonsmokers based on preliminary research results of Dr

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These results suggest that PNE offspring have greater susceptibility to learn from drug-related conditional stimuli and produce alterations in neuronal plasticity that contribute towards drug abuse vulnerability

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