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Collectively, these responses in transcriptional programming and cellular composition are consistent with smoke exposure pushing tuft-like cells toward incomplete or compromised ionocyte or PNEC phenotypes, further supporting our proposed rare cell lineage

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Some readers may delight in Richardss sly have-it-all-ways self-regard, but for me the most winning sections of the book are the tales of his becoming, the way his close adolescent friendship with Jagger and their mutual love for their blues heroes rapidly led to the formation of the Greatest Rock-and-Roll Band in the World