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Key considerations for developing e-cigarette regulations that promote population health include the inherent harms and addictiveness of e-cigarettes, the continuous and rapid evolution of products, the emerging evidence on long-term health impacts, evidence around youth initiation, ongoing regulatory and monitoring capacity, and the availability of support for cessation and/or these products as a harm reduction product for smokers unwilling or unable to quit

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It also impairs the lungs natural cleaning system and allows foreign particles and harmful chemicals to accumulate in the respiratory tract

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Respir Res 14:97 Soulitzis N, Neofytou E, Psarrou M, Anagnostis A, Tavernarakis N, Siafakas N, Tzortzaki EG (2012) Downregulation of lung mitochondrial prohibitin in COPD

Lung adenocarcinoma associated with germline EGFR R776H variant: a case report and review of the literature