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Thats the point

When special equipment is required, implementation as a standard method by independent laboratories becomes difficult

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The potential risk with the combination of azathioprine or 6-mercaptopurine and HUMIRA should be carefully considered

Thus, as long as the amount of a toxin in the smoke of a test cigarette increased by less than the amount TPM increased in that cigarette, the ratio would drop even if both the toxin and TPM increased with the additives