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However, vaping liquid contains over 80 chemicals including nicotine, cancer-causing chemicals and toxic heavy metals such as nickel, tin and lead 7

7 However, decreased CYP2A6 activity may influence smoking and carcinogen exposure in any smoker, and the relationship of nicotine metabolism and CYP2A6 genotype to the lung cancer risk of smokers of European descent was recently established in the Transdisciplinary Research in Cancer of the Lung consortium genome-wide association study data set

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Because innate immune responses are key regulators of the pathogenesis of COPD, our observations suggest that acrolein-modified SP-A may be involved in CS-mediated suppression of innate immunity

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Benowitz told me that this is because the psychological aspect of what habitual smoking does to the human body is as powerful as the immediate physiological effects of the smoke