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Clinical studies, dermatological reports and real-world experiences offer insights into the before and after effects of tretinoin treatment: Acne Improvement : Tretinoin significantly reduces acne lesions, both inflammatory and non-inflammatory

Pneumonitis Appendix H provides a detailed CSP for pneumonitis, which is a rare but serious and potentially life-threatening irAE associated with PD-1 inhibitor therapy, typically emerging several months after treatment initiation (although it can occur at any time) (Dadu et al., 2016

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However, thyroid medicines can help prevent problems and are safe to take during pregnancy