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Tobacco smoke causes oxidative stress so that insufficient oxygen is supplied to the skin resulting in tissue ischaemia and blood vessel occlusion

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Nicotine is extremely addictive The main reason why it is so difficult to quit smoking is that nicotine is physically addictive

[10] In the United Kingdom, HM Revenue & Customs raised tobacco duty rates from 30 October 2024, applying the standard tobacco-duty escalator and increasing the duty rate for hand-rolling tobacco by an additional 10% (to 12% above the Retail Price Index)