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Differentially expressed genes upon miR-320d overexpression are involved in the IL-1/NF-B signaling Since we previously observed that miR-320d is able to reduce IL-1-induced activation of the pro-inflammatory factor NF-B [14], we specifically investigated expression of ERK, IKBKB, IRAK1-4, JNK, MAP3K7, MYD88, p38, TAB1, TAB2 and TRAF6, genes involved in this pathway [22]

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Murphy is joined in Oppenheimer by Florence Pugh, Emily Blunt, Matt Damon, Robert Downey Jr., Josh Hartnett, Casey Affleck, Rami Malek and Kenneth Branagh