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We hypothesized that the persistent accumulation of fibrosis elevated ECM stiffness and impaired lung regeneration by supporting the inflammatory environment and changing the cell profile

Appendectomy also did not increase risk of CRC: Sakaue S(OR:1.382, 95%CI:0.301-6.352, P=0.678)

Biochim Biophys Acta 1984

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Although no statistically significant differences were found in the total sample, the study reported a subgroup of 9 children who exhibited clinically significant responses when taking the active treatment