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The central tobacco factory once stood in what is now the Plaza Cristo de Burgos but by the 18th century, as demand for tobacco products grew, it became apparent Seville needed a new location for production

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circumvent a standard tobacco-industry tactic"document dumping." If a company is subpoenaed for documents related to nicotine studies, it is common in the industry to respond "by driving a tractor-trailer to Washington and leaving 10 tons of documents at your door," according to a close associate of the F.D.A